Luisa Mestroni Selected Research

Connectin

1/2022	Association of Titin Variations With Late-Onset Dilated Cardiomyopathy.
12/2021	Clinical and genetic features of arrhythmogenic cardiomyopathy: diagnosis, management and the heart failure perspective.
11/2021	Prevalence and Evolution of Right Ventricular Dysfunction Among Different Genetic Backgrounds in Dilated Cardiomyopathy.
1/2021	The Sarcomeric Spring Protein Titin: Biophysical Properties, Molecular Mechanisms, and Genetic Mutations Associated with Heart Failure and Cardiomyopathy.
10/2020	Understanding the role of titin in dilated cardiomyopathy.
8/2020	Modifications of Titin Contribute to the Progression of Cardiomyopathy and Represent a Therapeutic Target for Treatment of Heart Failure.
1/2019	The Giant Protein Titin's Role in Cardiomyopathy: Genetic, Transcriptional, and Post-translational Modifications of TTN and Their Contribution to Cardiac Disease.
1/2016	A Review of the Giant Protein Titin in Clinical Molecular Diagnostics of Cardiomyopathies.
11/2015	Role of Titin Missense Variants in Dilated Cardiomyopathy.
10/2014	Titin and desmosomal genes in the natural history of arrhythmogenic right ventricular cardiomyopathy.

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Luisa Mestroni Research Topics

Disease

31	Cardiomyopathies (Cardiomyopathy) 03/2022 - 10/2004
20	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2022 - 03/2003
19	Heart Failure 01/2022 - 01/2004
7	Cardiac Sudden Death (Sudden Cardiac Arrest) 11/2021 - 08/2011
7	Sudden Death 10/2016 - 04/2004
6	Ventricular Tachycardia 01/2022 - 12/2014
6	Fibrosis (Cirrhosis) 12/2021 - 02/2012
5	Neoplasms (Cancer) 09/2021 - 12/2014
5	Laminopathies 01/2021 - 01/2018
4	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 10/2021 - 01/2007
4	Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy) 07/2021 - 08/2011
4	Glycogen Storage Disease Type IIb 03/2017 - 01/2004
4	Hypertension (High Blood Pressure) 05/2014 - 04/2004
3	Disease Progression 10/2021 - 11/2015
2	Edema (Dropsy) 03/2022 - 12/2021
2	Left Ventricular Dysfunction 12/2021 - 11/2015
2	Cardiac Arrhythmias (Arrythmia) 01/2020 - 01/2020
2	Myocardial Infarction 05/2019 - 01/2018
2	Ventricular Fibrillation 01/2019 - 03/2008
2	Atrial Fibrillation 01/2019 - 06/2003
2	Muscular Diseases (Myopathy) 09/2015 - 01/2007
2	Muscular Dystrophies (Muscular Dystrophy) 01/2015 - 04/2002
2	Sinus Tachycardia 04/2004 - 04/2004
1	Atrioventricular Block 01/2022
1	Cardiotoxicity 09/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) 01/2020
1	Ectodermal Dysplasia (Aplasia Cutis Congenita) 01/2020
1	Heart Diseases (Heart Disease) 01/2019
1	Skin Diseases (Skin Disease) 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2014
1	Dyslipidemias (Dyslipidemia) 05/2014
1	Hypertrophy 07/2013

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 12/2021 - 12/2005
13	ConnectinIBA 01/2022 - 08/2011
8	Lamin Type A (Lamin A)IBA 01/2022 - 03/2003
6	LaminsIBA 01/2020 - 12/2005
5	FilaminsIBA 02/2022 - 01/2018
4	Biological ProductsIBA 01/2021 - 11/2015
3	GadoliniumIBA 03/2022 - 11/2015
3	PlakophilinsIBA 10/2021 - 12/2019
3	Biomarkers (Surrogate Marker)IBA 11/2019 - 11/2015
3	Sodium Channels (Sodium Channel)IBA 01/2017 - 10/2004
3	Endothelin Receptors (Endothelin Receptor)IBA 05/2014 - 01/2011
2	Valsartan (Vals)FDA Link 10/2021 - 12/2019
2	Amiodarone (Amiodarona)FDA LinkGeneric 07/2021 - 05/2011
2	DystrophinIBA 08/2020 - 01/2007
2	Desmoplakins (Desmoplakin)IBA 01/2020 - 01/2018
2	Lysosomal Membrane ProteinsIBA 03/2017 - 01/2016
2	beta Adrenergic ReceptorsIBA 06/2011 - 01/2011
2	alpha Adrenergic ReceptorsIBA 06/2011 - 01/2011
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 04/2004 - 04/2004
1	phospholambanIBA 12/2021
1	Messenger RNA (mRNA)IBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	C.I. direct red 80IBA 11/2021
1	Antineoplastic Agents (Antineoplastics)IBA 09/2021
1	AnthracyclinesIBA 09/2021
1	Sotalol (Sotalol Hydrochloride)FDA LinkGeneric 07/2021
1	Anti-Arrhythmia AgentsIBA 07/2021
1	Metalloproteases (Metalloproteinases)IBA 01/2021
1	DisintegrinsIBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	PolymersIBA 05/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019
1	E2F Transcription FactorsIBA 01/2019
1	AnkyrinsIBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 01/2018
1	HydrogelsIBA 01/2018
1	AlginatesIBA 01/2018
1	CalciumIBA 02/2017
1	Adenosine Triphosphatases (ATPase)IBA 02/2017
1	PeriostinIBA 01/2017
1	Troponin IIBA 01/2017
1	Galectin 3 (LGALS3)IBA 01/2017
1	pro-brain natriuretic peptide (1-76)IBA 01/2017
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2017
1	Procollagen Type IIBA 01/2017
1	collagen type I trimeric cross-linked peptideIBA 01/2017
1	Protein Isoforms (Isoforms)IBA 01/2016
1	Carbon Nanotubes (Carbon Nanotube)IBA 12/2014
1	Pharmaceutical PreparationsIBA 05/2014
1	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2014
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 07/2013
1	Atrial Natriuretic Factor (ANF)IBA 07/2013
1	Troponin T (Troponin T1)IBA 01/2013

Therapy/Procedure

14	Therapeutics 03/2022 - 06/2008
8	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 12/2021 - 04/2004
7	Heart Transplantation (Grafting, Heart) 11/2021 - 01/2004
3	Precision Medicine 01/2021 - 01/2011
2	Drug Therapy (Chemotherapy) 09/2021 - 07/2006
2	Radiotherapy 09/2021 - 01/2021
2	Heart-Assist Devices 01/2020 - 01/2019
1	Cardiac Resynchronization Therapy 01/2022
1	Hematopoietic Stem Cell Transplantation 09/2021
1	Defibrillators (Defibrillator) 01/2019
1	Injections 01/2018
1	Secondary Prevention 12/2014
1	Catheter Ablation 12/2014